The tools of molecular biology
The whole genome of an organism can be up to billions of base pairs long, and so is difficult to work with
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Breaking the genome up into smaller fragments, each between 200-2000bp in size, can be done in a number of ways
Smaller pieces are clonable (inserted into a plasmid, and propagated in a bacterial cell)
Next came the technologies to manipulate and study DNA, for example, DNA cloning. |
