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Population types for QTL mapping (1)

There are many possible types of populations that can be used for QTL mapping. Here we compare a few of the most widely used:

Backcross (BC):

Advantages: it is easier to identify QTL as there are less epistatic and linkage drag effects; especially useful for crosses with wild species

Disadvantages: difficult or impossible in species that are highly heterozygous and outcrossing; best when inbred lines are available

Example: Huang XQ, Cöster H, Ganal MW, Röder MS (2003) Advanced backcross QTL analysis for the identification of quantitative trait loci alleles from wild relatives of wheat (Triticum aestivum L.). Theoretical Applied Genetics 106: 1379-1389.

See also: Tanksley and Nelson 1996