Methods/criteria for identifying orthologs
Methods/criteria for identifying orthologs
Hybridization: If a gene probe identifies (through Southern
hybridization) a single copy in two related diploid species, it is
assumed that the gene is orthologous in those two species.
In a paralogous gene family, many homologous copies are present in the genome of a single species. (Many genes fall into such multigene families, which makes the identification of orthologs between species quite hard.)
